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Ivermectin suppresses tumour growth and metastasis through degradation of PAK1 in oesophageal squamous cell carcinoma

Oesophageal squamous cell carcinoma (ESCC), the most common form of oesophageal malignancies in the Asia‐Pacific region, remains a major clinical challenge. In this study, we found that ivermectin, an effective antiparasitic drug that has been approved for patients to orally treat onchocerciasis for...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Bi, Shuning, Wei, Qiuren, Zhao, Zhijun, Wang, Chaojie, Xie, Songqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205794/
https://www.ncbi.nlm.nih.gov/pubmed/32237037
http://dx.doi.org/10.1111/jcmm.15195