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Generating low immunogenic pig pancreatic islet cell clusters for xenotransplantation

Xenotransplantation of pancreatic islets offers a promising alternative to overcome the shortage of allogeneic donors. Despite significant advances, either immune rejection or oxygen supply in immune protected encapsulated islets remains major bottlenecks for clinical application. To decrease xenoge...

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Detalles Bibliográficos
Autores principales: Carvalho Oliveira, Marco, Valdivia, Emilio, Verboom, Murielle, Yuzefovych, Yuliia, Sake, Hendrik Johannes, Pogozhykh, Olena, Niemann, Heiner, Schwinzer, Reinhard, Petersen, Björn, Seissler, Jochen, Blasczyk, Rainer, Figueiredo, Constança
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205796/
https://www.ncbi.nlm.nih.gov/pubmed/32212307
http://dx.doi.org/10.1111/jcmm.15136