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Isopropyl‐phloroglucinol‐DHA protects outer retinal cells against lethal dose of all‐trans‐retinal

All‐trans‐retinal (atRAL) is a highly reactive carbonyl specie, known for its reactivity on cellular phosphatidylethanolamine in photoreceptor. It is generated by photoisomerization of 11‐cis‐retinal chromophore linked to opsin by the Schiff's base reaction. In ABCA4‐associated autosomal recess...

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Detalles Bibliográficos
Autores principales: Cubizolle, Aurélie, Cia, David, Moine, Espérance, Jacquemot, Nathalie, Guillou, Laurent, Rosell, Mélissa, Angebault‐Prouteau, Claire, Lenaers, Guy, Meunier, Isabelle, Vercauteren, Joseph, Durand, Thierry, Crauste, Céline, Brabet, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205824/
https://www.ncbi.nlm.nih.gov/pubmed/32212312
http://dx.doi.org/10.1111/jcmm.15135