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FGF21 induces autophagy‐mediated cholesterol efflux to inhibit atherogenesis via RACK1 up‐regulation

Fibroblast growth factor 21 (FGF21) acts as an anti‐atherosclerotic agent. However, the specific mechanisms governing this regulatory activity are unclear. Autophagy is a highly conserved cell stress response which regulates atherosclerosis (AS) by reducing lipid droplet degradation in foam cells. W...

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Detalles Bibliográficos
Autores principales: Xiaolong, Lin, Dongmin, Guo, Liu, Mihua, Zuo, Wang, Huijun, Hu, Qiufen, Tan, XueMei, Hu, Wensheng, Lin, Yuping, Pan, Jun, Lin, Zhaolin, Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205825/
https://www.ncbi.nlm.nih.gov/pubmed/32227589
http://dx.doi.org/10.1111/jcmm.15118