QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism

Quaking (QKI), an RNA-binding protein, has been reported to exhibit numerous biological functions, such as mRNA regulation, cancer suppression, and anti-inflammation. However, little known about the effects of QKI on bone metabolism. In this study, we used a monocyte/macrophage-specific QKI knockout...

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Detalles Bibliográficos
Autores principales: Du, Tianshu, Yan, Zhao, Zhu, Shu, Chen, Guo, Wang, Li, Ye, Zichen, Wang, Wenwen, Zhu, Qingsheng, Lu, Zifan, Cao, Xiaorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205892/
https://www.ncbi.nlm.nih.gov/pubmed/32382069
http://dx.doi.org/10.1038/s41419-020-2548-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205892/
https://www.ncbi.nlm.nih.gov/pubmed/32382069
http://dx.doi.org/10.1038/s41419-020-2548-3

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