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MUC15 inhibits cancer metastasis via PI3K/AKT signaling in renal cell carcinoma

Patients with renal cell carcinoma (RCC) often develop distant metastasis and the specific molecular mechanism remains poorly understood. In our study, we demonstrated that MUC15, a subtype of mucins family, could suppress the progression of RCC by inhibiting PI3K/AKT signaling. Firstly, we observed...

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Detalles Bibliográficos
Autores principales: Yue, Yangyang, Hui, Ke, Wu, Shiqi, Zhang, Mengzhao, Que, Taotao, Gu, Yanan, Wang, Xinyang, Wu, Kaijie, Fan, Jinhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205982/
https://www.ncbi.nlm.nih.gov/pubmed/32382053
http://dx.doi.org/10.1038/s41419-020-2518-9