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TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple

Chemotherapy resistance is the major cause of nasopharyngeal carcinoma (NPC) treatment failure. Tripartite motif-containing protein (TRIM) family members play important roles in tumor development and chemotherapy failure. Here, based on a screening analysis of 71 TRIM family members by qRT-PCR, we f...

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Detalles Bibliográficos
Autores principales: Zhang, Runa, Li, Si-Wei, Liu, Lijuan, Yang, Jun, Huang, Guofu, Sang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206012/
https://www.ncbi.nlm.nih.gov/pubmed/32382014
http://dx.doi.org/10.1038/s41389-020-0229-9