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Prmt7 promotes myoblast differentiation via methylation of p38MAPK on arginine residue 70

MyoD functions as a master regulator to induce muscle-specific gene expression and myogenic differentiation. Here, we demonstrate a positive role of Protein arginine methyltransferase 7 (Prmt7) in MyoD-mediated myoblast differentiation through p38MAPK activation. Prmt7 depletion in primary or C2C12...

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Detalles Bibliográficos
Autores principales: Jeong, Hyeon-Ju, Lee, Sang-Jin, Lee, Hye-Jin, Kim, Hye-Been, Anh Vuong, Tuan, Cho, Hana, Bae, Gyu-Un, Kang, Jong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206020/
https://www.ncbi.nlm.nih.gov/pubmed/31243342
http://dx.doi.org/10.1038/s41418-019-0373-y