ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells

To discover novel therapeutic targets for triple-negative breast cancer (TNBC) and cancer stem cells (CSCs), we screened long non-coding RNAs (lncRNAs) most enriched in TNBCs for high expression in CSCs defined by high Aldefluor activity and associated with worse patient outcomes. This led to the id...

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Detalles Bibliográficos
Autores principales: Vidovic, Dejan, Huynh, Thomas T., Konda, Prathyusha, Dean, Cheryl, Cruickshank, Brianne M., Sultan, Mohammad, Coyle, Krysta M., Gujar, Shashi, Marcato, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206030/
https://www.ncbi.nlm.nih.gov/pubmed/31197235
http://dx.doi.org/10.1038/s41418-019-0362-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206030/
https://www.ncbi.nlm.nih.gov/pubmed/31197235
http://dx.doi.org/10.1038/s41418-019-0362-1

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