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PATH - Prediction of Amyloidogenicity by Threading and Machine Learning
Amyloids are protein aggregates observed in several diseases, for example in Alzheimer’s and Parkinson’s diseases. An aggregate has a very regular beta structure with a tightly packed core, which spontaneously assumes a steric zipper form. Experimental methods enable studying such peptides, however...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206081/ https://www.ncbi.nlm.nih.gov/pubmed/32382058 http://dx.doi.org/10.1038/s41598-020-64270-3 |