Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity

A majority of the world’s population is infected with HSV-1, highlighting the need for vaccines that are effective in HSV-1-seropositive hosts. We established a superinfection model by infecting mice intranasally with a sublethal dose of HSV-1, which results in high rates of seropositive, latently i...

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Detalles Bibliográficos
Autores principales: Burn Aschner, Clare, Knipe, David M., Herold, Betsy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206093/
https://www.ncbi.nlm.nih.gov/pubmed/32411398
http://dx.doi.org/10.1038/s41541-020-0184-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206093/
https://www.ncbi.nlm.nih.gov/pubmed/32411398
http://dx.doi.org/10.1038/s41541-020-0184-7

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