The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53

Ubiquitin-specific peptidase 10 (USP10) stabilizes both tumor suppressors and oncogenes in a context-dependent manner. However, the nature of USP10’s role in non-small cell lung cancer (NSCLC) remains unclear. By analyzing The Cancer Genome Atlas (TCGA) database, we have shown that high levels of US...

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Detalles Bibliográficos
Autores principales: Hu, Chen, Zhang, Mu, Moses, Niko, Hu, Cong-li, Polin, Lisa, Chen, Wei, Jang, Hyejeong, Heyza, Joshua, Malysa, Agnes, Caruso, Joseph A., Xiang, Shengyan, Patrick, Steve, Stemmer, Paul, Lou, Zhenkun, Bai, Wenlong, Wang, Chuangui, Bepler, Gerold, Zhang, Xiaohong Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206099/
https://www.ncbi.nlm.nih.gov/pubmed/32382008
http://dx.doi.org/10.1038/s41419-020-2519-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206099/
https://www.ncbi.nlm.nih.gov/pubmed/32382008
http://dx.doi.org/10.1038/s41419-020-2519-8

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