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LGR5(+) epithelial tumor stem-like cells generate a 3D-organoid model for ameloblastoma
Ameloblastoma (AM) is a benign but locally aggressive tumor with high recurrences. Currently, underlying pathophysiology remains elusive, and radical surgery remains the most definitive treatment with severe morbidities. We have recently reported that AM harbors a subpopulation of tumor epithelial s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206107/ https://www.ncbi.nlm.nih.gov/pubmed/32382005 http://dx.doi.org/10.1038/s41419-020-2560-7 |