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LGR5(+) epithelial tumor stem-like cells generate a 3D-organoid model for ameloblastoma

Ameloblastoma (AM) is a benign but locally aggressive tumor with high recurrences. Currently, underlying pathophysiology remains elusive, and radical surgery remains the most definitive treatment with severe morbidities. We have recently reported that AM harbors a subpopulation of tumor epithelial s...

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Detalles Bibliográficos
Autores principales: Chang, Ting-Han, Shanti, Rabie M., Liang, Yanfang, Zeng, Jincheng, Shi, Shihong, Alawi, Faizan, Carrasco, Lee, Zhang, Qunzhou, Le, Anh D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206107/
https://www.ncbi.nlm.nih.gov/pubmed/32382005
http://dx.doi.org/10.1038/s41419-020-2560-7