βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1

Cellular DNA is constantly under threat from internal and external insults, consequently multiple pathways have evolved to maintain chromosomal fidelity. Our previous studies revealed that chronic stress, mediated by continuous stimulation of the β(2)-adrenergic-βarrestin-1 signaling axis suppresses...

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Detalles Bibliográficos
Autores principales: Nieto, Ainhoa, Hara, Makoto R., Quereda, Victor, Grant, Wayne, Saunders, Vanessa, Xiao, Kunhong, McDonald, Patricia H., Duckett, Derek R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206116/
https://www.ncbi.nlm.nih.gov/pubmed/31506606
http://dx.doi.org/10.1038/s41418-019-0406-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206116/
https://www.ncbi.nlm.nih.gov/pubmed/31506606
http://dx.doi.org/10.1038/s41418-019-0406-6

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