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Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers

Alterations of adult neurogenesis have been reported in several Alzheimer's disease (AD) animal models and human brains, while defects in this process at presymptomatic/early stages of AD have not been explored yet. To address this, we investigated potential neurogenesis defects in Tg2576 trans...

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Detalles Bibliográficos
Autores principales: Scopa, Chiara, Marrocco, Francesco, Latina, Valentina, Ruggeri, Federica, Corvaglia, Valerio, La Regina, Federico, Ammassari-Teule, Martine, Middei, Silvia, Amadoro, Giuseppina, Meli, Giovanni, Scardigli, Raffaella, Cattaneo, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206128/
https://www.ncbi.nlm.nih.gov/pubmed/31591472
http://dx.doi.org/10.1038/s41418-019-0409-3