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Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers
Alterations of adult neurogenesis have been reported in several Alzheimer's disease (AD) animal models and human brains, while defects in this process at presymptomatic/early stages of AD have not been explored yet. To address this, we investigated potential neurogenesis defects in Tg2576 trans...
Autores principales: | Scopa, Chiara, Marrocco, Francesco, Latina, Valentina, Ruggeri, Federica, Corvaglia, Valerio, La Regina, Federico, Ammassari-Teule, Martine, Middei, Silvia, Amadoro, Giuseppina, Meli, Giovanni, Scardigli, Raffaella, Cattaneo, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206128/ https://www.ncbi.nlm.nih.gov/pubmed/31591472 http://dx.doi.org/10.1038/s41418-019-0409-3 |
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