Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer’s disease

Amyloid-β (Aβ) oligomers largely initiate the cascade underlying the pathology of Alzheimer’s disease (AD). Galectin-3 (Gal-3), which is a member of the galectin protein family, promotes inflammatory responses and enhances the homotypic aggregation of cancer cells. Here, we examined the role and act...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Chih-Chieh, Cheng, Kuang-Min, Ma, Yun-Li, Hsu, Wei-Lun, Chen, Yan-Chu, Fuh, Jong-Ling, Lee, Wei-Ju, Chao, Chih-Chang, Lee, Eminy H. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206130/
https://www.ncbi.nlm.nih.gov/pubmed/31127200
http://dx.doi.org/10.1038/s41418-019-0348-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206130/
https://www.ncbi.nlm.nih.gov/pubmed/31127200
http://dx.doi.org/10.1038/s41418-019-0348-z

Ejemplares similares