RAF kinases are stabilized and required for dendritic cell differentiation and function

RAF kinases (ARAF, BRAF, and CRAF) are highly conserved enzymes that trigger the RAF-MEK1/2-ERK1/2 (MAPK) pathway upon activation of RAS. Despite enormous clinical interest, relatively little is known on the role of RAFs in mediating immune responses. Here, we investigated the role of RAF kinases an...

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Detalles Bibliográficos
Autores principales: Riegel, Kristina, Schlöder, Janine, Sobczak, Marco, Jonuleit, Helmut, Thiede, Bernd, Schild, Hansjörg, Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206131/
https://www.ncbi.nlm.nih.gov/pubmed/31541179
http://dx.doi.org/10.1038/s41418-019-0416-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206131/
https://www.ncbi.nlm.nih.gov/pubmed/31541179
http://dx.doi.org/10.1038/s41418-019-0416-4

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