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LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motor neurons. Improving neuronal survival in ALS remains a significant challenge. Previously, we identified Lanthionine synthetase C-like protein 1 (LanCL1) as a neuronal antioxidant defens...

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Detalles Bibliográficos
Autores principales: Tan, Honglin, Chen, Mina, Pang, Dejiang, Xia, Xiaoqiang, Du, Chongyangzi, Yang, Wanchun, Cui, Yiyuan, Huang, Chao, Jiang, Wanxiang, Bi, Dandan, Li, Chunyu, Shang, Huifang, Worley, Paul F., Xiao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206132/
https://www.ncbi.nlm.nih.gov/pubmed/31570855
http://dx.doi.org/10.1038/s41418-019-0422-6