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LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motor neurons. Improving neuronal survival in ALS remains a significant challenge. Previously, we identified Lanthionine synthetase C-like protein 1 (LanCL1) as a neuronal antioxidant defens...
Autores principales: | Tan, Honglin, Chen, Mina, Pang, Dejiang, Xia, Xiaoqiang, Du, Chongyangzi, Yang, Wanchun, Cui, Yiyuan, Huang, Chao, Jiang, Wanxiang, Bi, Dandan, Li, Chunyu, Shang, Huifang, Worley, Paul F., Xiao, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206132/ https://www.ncbi.nlm.nih.gov/pubmed/31570855 http://dx.doi.org/10.1038/s41418-019-0422-6 |
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