ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice

Defective rhodopsin homeostasis is one of the major causes of retinal degeneration, including the disease Retinitis pigmentosa. To identify cellular factors required for the biosynthesis of rhodopsin, we performed a genome-wide genetic screen in Drosophila for mutants with reduced levels of rhodopsi...

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Detalles Bibliográficos
Autores principales: Xiong, Liangyao, Zhang, Lin, Yang, Yeming, Li, Na, Lai, Wenjia, Wang, Fengchao, Zhu, Xianjun, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206144/
https://www.ncbi.nlm.nih.gov/pubmed/31263175
http://dx.doi.org/10.1038/s41418-019-0378-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206144/
https://www.ncbi.nlm.nih.gov/pubmed/31263175
http://dx.doi.org/10.1038/s41418-019-0378-6

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