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The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth

β-transducin repeat-containing protein (β-TrCP), one of the best-characterized substrate recognition components of the SKP1-CUL1-F-box (SCF) E3 ligase, has two distinct paralogs, β-TrCP1 and β-TrCP2, expressed in mammals. Through governing the ubiquitination and degradation of numerous key regulator...

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Detalles Bibliográficos
Autores principales: Cui, Danrui, Dai, Xiaoqing, Shu, Jianfeng, Ma, Ying, Wei, Dongping, Xiong, Xiufang, Zhao, Yongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206145/
https://www.ncbi.nlm.nih.gov/pubmed/31406304
http://dx.doi.org/10.1038/s41418-019-0402-x