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CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity

Centrosomal P4.1-associated protein (CPAP) is overexpressed in hepatocellular carcinoma (HCC) and positively correlated with recurrence and vascular invasion. Here, we found that CPAP plays an important role in HCC malignancies. Functional characterization indicated that CPAP overexpression increase...

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Detalles Bibliográficos
Autores principales: Chen, Ruo-Yu, Yen, Chia-Jui, Liu, Yao-Wen, Guo, Chun-Guo, Weng, Chieh-Yu, Lai, Chien-Hsien, Wang, Ju-Ming, Lin, Yih-Jyh, Hung, Liang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206147/
https://www.ncbi.nlm.nih.gov/pubmed/31511651
http://dx.doi.org/10.1038/s41418-019-0413-7