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TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin

Metastasis is one of the main contributors to the poor prognosis of hepatocellular carcinoma (HCC). However, the underlying mechanism of HCC metastasis remains largely unknown. Here, we showed that TXNDC12, a thioredoxin-like protein, was upregulated in highly metastatic HCC cell lines as well as in...

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Detalles Bibliográficos
Autores principales: Yuan, Kefei, Xie, Kunlin, Lan, Tian, Xu, Lin, Chen, Xiangzheng, Li, Xuefeng, Liao, Mingheng, Li, Jiaxin, Huang, Jiwei, Zeng, Yong, Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206186/
https://www.ncbi.nlm.nih.gov/pubmed/31570854
http://dx.doi.org/10.1038/s41418-019-0421-7