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Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice
BACKGROUND/AIMS: Intestinal fibrosis is a major complication of Crohn’s disease (CD). The profibrotic protein transforming growth factor-β (TGF-β) has been considered to be critical for the induction of the fibrotic program. TGF-β has the ability to induce not only the expression of extracellular ma...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association for the Study of Intestinal Diseases
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206341/ https://www.ncbi.nlm.nih.gov/pubmed/32050315 http://dx.doi.org/10.5217/ir.2019.00037 |