Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma

In this study, we have surface-functionalized PEGylated-nanoliposomal doxorubicin (DOX) with anti-EpCAM (epithelial cell adhesion molecule) aptamer via post-insertion of anti-EpCAM aptamer-conjugated DSPE-mPEG(2000) into Caelyx® (ED-lip). The size, charge, release profile, and cytotoxicity and cellu...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashreghi, Mohammad, Zamani, Parvin, Moosavian, Seyedeh Alia, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206479/
https://www.ncbi.nlm.nih.gov/pubmed/32383027
http://dx.doi.org/10.1186/s11671-020-03334-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206479/
https://www.ncbi.nlm.nih.gov/pubmed/32383027
http://dx.doi.org/10.1186/s11671-020-03334-9

Ejemplares similares