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Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma

In this study, we have surface-functionalized PEGylated-nanoliposomal doxorubicin (DOX) with anti-EpCAM (epithelial cell adhesion molecule) aptamer via post-insertion of anti-EpCAM aptamer-conjugated DSPE-mPEG(2000) into Caelyx® (ED-lip). The size, charge, release profile, and cytotoxicity and cellu...

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Detalles Bibliográficos
Autores principales:	Mashreghi, Mohammad, Zamani, Parvin, Moosavian, Seyedeh Alia, Jaafari, Mahmoud Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Nano Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206479/ https://www.ncbi.nlm.nih.gov/pubmed/32383027 http://dx.doi.org/10.1186/s11671-020-03334-9

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