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Dynamic nature of somatic chromosomal mosaicism, genetic-environmental interactions and therapeutic opportunities in disease and aging

BACKGROUND: Somatic chromosomal mosaicism is the presence of cell populations differing with respect to the chromosome complements (e.g. normal and abnormal) in an individual. Chromosomal mosaicism is associated with a wide spectrum of disease conditions and aging. Studying somatic genome variations...

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Detalles Bibliográficos
Autores principales: Vorsanova, Svetlana G., Yurov, Yuri B., Iourov, Ivan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206664/
https://www.ncbi.nlm.nih.gov/pubmed/32411302
http://dx.doi.org/10.1186/s13039-020-00488-0