Common biochemical properties of metabolic genes recurrently dysregulated in tumors

BACKGROUND: Tumor initiation and progression are associated with numerous metabolic alterations. However, the biochemical drivers and constraints that contribute to metabolic gene dysregulation are unclear. METHODS: Here, we present MetOncoFit, a computational model that integrates 142 metabolic fea...

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Detalles Bibliográficos
Autores principales: Oruganty, Krishnadev, Campit, Scott Edward, Mamde, Sainath, Lyssiotis, Costas A., Chandrasekaran, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206696/
https://www.ncbi.nlm.nih.gov/pubmed/32411371
http://dx.doi.org/10.1186/s40170-020-0211-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206696/
https://www.ncbi.nlm.nih.gov/pubmed/32411371
http://dx.doi.org/10.1186/s40170-020-0211-1

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