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Common biochemical properties of metabolic genes recurrently dysregulated in tumors
BACKGROUND: Tumor initiation and progression are associated with numerous metabolic alterations. However, the biochemical drivers and constraints that contribute to metabolic gene dysregulation are unclear. METHODS: Here, we present MetOncoFit, a computational model that integrates 142 metabolic fea...
Autores principales: | Oruganty, Krishnadev, Campit, Scott Edward, Mamde, Sainath, Lyssiotis, Costas A., Chandrasekaran, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206696/ https://www.ncbi.nlm.nih.gov/pubmed/32411371 http://dx.doi.org/10.1186/s40170-020-0211-1 |
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