Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease

BACKGROUND: Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of neuroinflammation. However, microglial proteomics studies have been limited by low cellular yield and contamination by non-microglial proteins using existing en...

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Detalles Bibliográficos
Autores principales: Rayaprolu, Sruti, Gao, Tianwen, Xiao, Hailian, Ramesha, Supriya, Weinstock, Laura D., Shah, Jheel, Duong, Duc M., Dammer, Eric B., Webster, James A., Lah, James J., Wood, Levi B., Betarbet, Ranjita, Levey, Allan I., Seyfried, Nicholas T., Rangaraju, Srikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206797/
https://www.ncbi.nlm.nih.gov/pubmed/32381088
http://dx.doi.org/10.1186/s13024-020-00377-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206797/
https://www.ncbi.nlm.nih.gov/pubmed/32381088
http://dx.doi.org/10.1186/s13024-020-00377-5

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