GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation

BACKGROUND: Glucagon-like peptide-1 (GLP-1) induces diuresis and natriuresis. Previously we have shown that GLP-1 activates afferent renal nerve to increase efferent renal sympathetic nerve activity that negates the diuresis and natriuresis as a negative feedback mechanism in normal rats. However, r...

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Detalles Bibliográficos
Autores principales: Katsurada, Kenichi, Nandi, Shyam S., Zheng, Hong, Liu, Xuefei, Sharma, Neeru M., Patel, Kaushik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206815/
https://www.ncbi.nlm.nih.gov/pubmed/32384887
http://dx.doi.org/10.1186/s12933-020-01029-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206815/
https://www.ncbi.nlm.nih.gov/pubmed/32384887
http://dx.doi.org/10.1186/s12933-020-01029-0

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