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Dietary phytate lowers K-ras mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer

OBJECTIVE(S): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions. The present study was designed to determine whether dietary phytate affects mutation frequency in colon epithelial cells challenged with azoxymethane in vivo, through lowering the formation of...

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Detalles Bibliográficos
Autores principales: Pallem, Poorna Venkata Satya Prasad, Bodiga, Sreedhar, Bodiga, Vijaya Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206830/
https://www.ncbi.nlm.nih.gov/pubmed/32405345
http://dx.doi.org/10.22038/IJBMS.2019.34374.8161