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Dietary phytate lowers K-ras mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer
OBJECTIVE(S): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions. The present study was designed to determine whether dietary phytate affects mutation frequency in colon epithelial cells challenged with azoxymethane in vivo, through lowering the formation of...
Autores principales: | Pallem, Poorna Venkata Satya Prasad, Bodiga, Sreedhar, Bodiga, Vijaya Lakshmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206830/ https://www.ncbi.nlm.nih.gov/pubmed/32405345 http://dx.doi.org/10.22038/IJBMS.2019.34374.8161 |
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