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BK(Ca) Mediates Dysfunction in High Glucose Induced Mesangial Cell Injury via TGF-β1/Smad2/3 Signaling Pathways

OBJECTIVE: To explore the role and mechanism of BK(Ca) in diabetic kidney disease. METHODS: Rat mesangial cells (MCs) HBZY-1 were cultured with high glucose to simulate the high-glucose environment of diabetic kidney disease in vivo. The effects of large conductance calcium-activated potassium chann...

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Detalles Bibliográficos
Autores principales: Wu, Zhigui, Yin, Wenxian, Sun, Mengqi, Si, Yuankai, Wu, Xiaoxiao, Chen, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206888/
https://www.ncbi.nlm.nih.gov/pubmed/32411221
http://dx.doi.org/10.1155/2020/3260728