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Chitosan-Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation and immunogenic cell death of eukaryotic cells. We have previously demonstrat...

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Detalles Bibliográficos
Autores principales: Robles-Planells, Claudia, Sánchez-Guerrero, Giselle, Barrera-Avalos, Carlos, Matiacevich, Silvia, Rojo, Leonel E., Pavez, Jorge, Salas-Huenuleo, Edison, Kogan, Marcelo J., Escobar, Alejandro, Milla, Luis A., Fernandez, Ricardo, Imarai, Mónica, Spencer, Eugenio, Huidobro-Toro, Juan Pablo, Acuña-Castillo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206890/
https://www.ncbi.nlm.nih.gov/pubmed/32410869
http://dx.doi.org/10.1155/2020/8680692