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Pretreatment with adalimumab reduces ventilator-induced lung injury in an experimental model

OBJECTIVE: To determine whether adalimumab administration before mechanical ventilation reduces ventilator-induced lung injury (VILI). METHODS: Eighteen rats randomized into 3 groups underwent mechanical ventilation for 3 hours with a fraction of inspired oxygen = 0.40% including a low tidal volume...

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Detalles Bibliográficos
Autores principales: Correger, Enrique, Marcos, Josefina, Laguens, Graciela, Stringa, Pablo, Cardinal-Fernández, Pablo, Blanch, Lluis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206963/
https://www.ncbi.nlm.nih.gov/pubmed/32401991
http://dx.doi.org/10.5935/0103-507X.20200010