Cargando…

Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy

BACKGROUND: Immunogenic cell death (ICD) is a peculiar modality of cellular demise that elicits adaptive immune responses and triggers T cell-dependent immunity. METHODS: Fluorescent biosensors were employed for an unbiased drug screen approach aiming at the identification of ICD enhancers. RESULTS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan, Xie, Wei, Humeau, Juliette, Chen, Guo, Liu, Peng, Pol, Jonathan, Zhang, Zhen, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206967/
https://www.ncbi.nlm.nih.gov/pubmed/32221018
http://dx.doi.org/10.1136/jitc-2019-000462