PDE3 Inhibition Reduces Epithelial Mast Cell Numbers in Allergic Airway Inflammation and Attenuates Degranulation of Basophils and Mast Cells

Epithelial mast cells are generally present in the airways of patients with allergic asthma that are inadequately controlled. Airway mast cells (MCs) are critically involved in allergic airway inflammation and contribute directly to the main symptoms of allergic patients. Phosphodiesterase 3 (PDE3)...

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Detalles Bibliográficos
Autores principales: Beute, Jan, Ganesh, Keerthana, Nastiti, Hedwika, Hoogenboom, Robin, Bos, Vivica, Folkerts, Jelle, Schreurs, Marco W. J., Hockman, Steve, Hendriks, Rudi W., KleinJan, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206980/
https://www.ncbi.nlm.nih.gov/pubmed/32425769
http://dx.doi.org/10.3389/fphar.2020.00470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206980/
https://www.ncbi.nlm.nih.gov/pubmed/32425769
http://dx.doi.org/10.3389/fphar.2020.00470

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