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Resolving mechanisms of immune‐mediated disease in primary CD4 T cells

Deriving mechanisms of immune‐mediated disease from GWAS data remains a formidable challenge, with attempts to identify causal variants being frequently hampered by strong linkage disequilibrium. To determine whether causal variants could be identified from their functional effects, we adapted a mas...

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Detalles Bibliográficos
Autores principales: Bourges, Christophe, Groff, Abigail F, Burren, Oliver S, Gerhardinger, Chiara, Mattioli, Kaia, Hutchinson, Anna, Hu, Theodore, Anand, Tanmay, Epping, Madeline W, Wallace, Chris, Smith, Kenneth GC, Rinn, John L, Lee, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207160/
https://www.ncbi.nlm.nih.gov/pubmed/32239644
http://dx.doi.org/10.15252/emmm.202012112