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SUN-207 Modelling Long Term Glucocorticoid-Induced HPA Axis Suppression in Mice

Glucocorticoids are prescribed for >3 months to 1% of the UK population. 10-50% of these long-term glucocorticoid treated patients develop persistent HPA axis suppression associated with mortality and morbidity. We have developed a mouse model of glucocorticoid-induced HPA axis dysfunction to det...

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Detalles Bibliográficos
Autores principales: Romano, Nicola, Duncan, Peter James, Nolan, Oscar, Tissier, Paul Roussel Le, Shipston, Mike, Chambers, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207296/
http://dx.doi.org/10.1210/jendso/bvaa046.1797