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SAT-607 The Vagus Nerve and the Hypothalamus Mediate Different Aspects of the Anorectic Effects of PYY(3-36)

Background: Drugs that safely promote weight loss are required to treat the obesity crisis. The gut hormone peptide YY 3-36 (PYY(3-36)) is secreted post-prandially to suppress appetite via the Y2 receptor (Y2R). However, it is unclear whether PYY(3-36) acts directly on the Y2R in the hypothalamic ar...

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Detalles Bibliográficos
Autores principales: Alonso, Aldara Martin, Cork, Simon C, Ma, Yue, Arnold, Myrtha, Herzog, Herbert, Bloom, Stephen R, Distaso, Walter, Murphy, Kevin Graeme, Salem, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207319/
http://dx.doi.org/10.1210/jendso/bvaa046.1337