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SUN-345 Use of Anti-FGF23 Monoclonal Antibody in the Treatment of Children and Adolescents with X-Linked Hypophosphatemic Rickets

Background: X-linked hypophosphataemia is the most common heritable form of rickets in children, disorder caused by mutations in PHEX, leading to elevated secretion of FGF23, renal phosphate wasting with consequent hypophosphataemia, diminish synthesis of 1,25(OH)2 vitamin D, rickets/osteomalacia, a...

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Detalles Bibliográficos
Autores principales: Cassinelli, Hamilton Raul, Brenzoni, Luciana, Alconcher, Laura, Forclaz, Veronica, D′Amato, Silvia, Rozenfeld, Paula, Bergada, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207672/
http://dx.doi.org/10.1210/jendso/bvaa046.1363