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OR14-03 The Transcriptional Coactivation Function of EHMT2 Restricts Chronic Glucocorticoid Exposure Induced Insulin Resistance

Glucocorticoids are required for metabolic adaptations during times of stress. However, chronic glucocorticoid exposure is associated with metabolic disorders such as insulin resistance. Glucocorticoids mainly convey their signals through an intracellular glucocorticoid receptor (GR). GR is a transc...

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Detalles Bibliográficos
Autores principales: Lee, Rebecca Arwyn, Tsay, Ariel, Chang, Maggie, Li, Danielle, Wang, Jen-Chywan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207676/
http://dx.doi.org/10.1210/jendso/bvaa046.1176