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SAT-145 Cholesterol Uptake as a Critical Vulnerability in Triple Negative Breast Cancer

Triple Negative Breast Cancer (TNBC) is an aggressive subtype of cancer with poor prognosis due to high metastatic potential and lack of targeted therapies. Normal epithelial cells express the microRNA-200c (miR-200c), a potent suppressor of epithelial-to-mesenchymal transition (EMT). However, miR-2...

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Detalles Bibliográficos
Autor principal: O’Neill, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207914/
http://dx.doi.org/10.1210/jendso/bvaa046.1368