OR33-03 Congenital Leptin Deficiency: Clinical Insights from the First Reported US Cases

Background: Congenital leptin deficiency (CLD) is a rare autosomal recessive form of monogenic obesity caused by loss-of-function mutations in the leptin gene. Targeted therapy is available in the form of recombinant human leptin (metreleptin). Previous case series have reported dramatic weight loss...

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Detalles Bibliográficos
Autores principales: Torchen, Laura C, Hakamy, Beth, Gordon, Leo I, Marsh, Erica E, Yaseen, Nabeel R, Neff, Lisa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207930/
http://dx.doi.org/10.1210/jendso/bvaa046.1059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207930/
http://dx.doi.org/10.1210/jendso/bvaa046.1059

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