OR17-01 Leptin Decreases De Novo Lipogenesis in Lipodystrophic Patients

De novo lipogenesis (DNL) plays a role in the development of hepatic steatosis and non-alcoholic fatty liver disease (NAFLD). In rodent models of both health and lipodystrophy (LD), leptin decreases DNL. In human patients with LD, reduced adipose tissue results in adipokine deficiencies, including l...

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Detalles Bibliográficos
Autores principales: Baykal, Annah Petek, Parks, Elizabeth J, Shamburek, Robert, Chung, Stephanie, Syed-Abdul, Majid M, Muniyappa, Ranganath, Cochran, Elaine, Startzell, Megan, Gharib, Ahmed M, Ouwerkerk, Ronald, Walter, Peter J, Brown, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Cardiovascular Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207974/
http://dx.doi.org/10.1210/jendso/bvaa046.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207974/
http://dx.doi.org/10.1210/jendso/bvaa046.035

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