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OR17-01 Leptin Decreases De Novo Lipogenesis in Lipodystrophic Patients
De novo lipogenesis (DNL) plays a role in the development of hepatic steatosis and non-alcoholic fatty liver disease (NAFLD). In rodent models of both health and lipodystrophy (LD), leptin decreases DNL. In human patients with LD, reduced adipose tissue results in adipokine deficiencies, including l...
Autores principales: | Baykal, Annah Petek, Parks, Elizabeth J, Shamburek, Robert, Chung, Stephanie, Syed-Abdul, Majid M, Muniyappa, Ranganath, Cochran, Elaine, Startzell, Megan, Gharib, Ahmed M, Ouwerkerk, Ronald, Walter, Peter J, Brown, Rebecca J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207974/ http://dx.doi.org/10.1210/jendso/bvaa046.035 |
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