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SAT-300 Evading Death: Noxa in Cushing’s Disease Pituitary Adenomas

Introduction: Recurrence of Cushing’s disease (CD) caused by benign pituitary microadenomas are challenging clinical problems. Mechanisms underlying adenoma formation and recurrence remain unknown. PMAIP1 gene codes for Noxa, a Bcl-2 homology 3 (BH3) pro-apoptotic protein frequently downregulated in...

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Detalles Bibliográficos
Autores principales: Alvarez, Reinier, Floros, Konstantinos, Johnson, Kory, Elkahloun, Abdel, Wu, Weiwei, Edwards, Nancy, Chaudhury, Abhik Ray, Nieman, Lynnette, Stratakis, Constantine, Chittiboina, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208015/
http://dx.doi.org/10.1210/jendso/bvaa046.1312