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OR14-02 Circadian Regulation of Chromatin State Mediates Pancreatic Islet Incretin Response

The circadian clock is programmed by an autoregulatory transcription feedback loop present in brain and peripheral tissues that coordinates metabolism with nutritional state and the sleep-wake cycle. Epidemiologic and genetic studies indicate circadian disruption as a risk factor in the development...

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Detalles Bibliográficos
Autores principales: Weidemann, Benjamin John, Kobayashi, Mikoto Alfred, Marcheva, Biliana, Bass, Joseph T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7208137/
http://dx.doi.org/10.1210/jendso/bvaa046.1604